For what conditions is Verapamil hydrochloride indicated?

Verapamil hydrochloride is indicated for angina and hypertension, making the selection of this answer appropriate. As a calcium channel blocker, Verapamil works by inhibiting calcium ions from entering the cardiac and vascular smooth muscle cells, which leads to a decrease in heart rate and blood pressure.

In the treatment of angina, it helps to reduce the workload of the heart by decreasing oxygen demand due to lowered heart rate. Additionally, its ability to dilate blood vessels effectively lowers blood pressure, making it a key medication for managing hypertension.

While atrial fibrillation can indeed be treated with Verapamil, the inclusion of heart failure in that option is misleading as Verapamil is generally contraindicated in patients with heart failure due to its negative inotropic effects. Cholesterol management and treatment of chronic obstructive pulmonary disease are not indications for Verapamil either, as those conditions require different classes of drugs altogether.