In managing hypertension, what is the net effect of Enalapril Maleate?

Study for the 2PD Top 200 Drugs Anti-Infectives and Cardiovascular Agents Test. Access flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Enalapril Maleate is an angiotensin-converting enzyme (ACE) inhibitor that is primarily used in the treatment of hypertension. Its mechanism of action involves blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. By inhibiting this conversion, Enalapril leads to vasodilation, which lowers peripheral vascular resistance and ultimately reduces blood pressure.

In addition to lowering blood pressure, Enalapril can also have beneficial effects on heart function and reduce the risk of heart failure by decreasing the workload on the heart. It promotes increased excretion of sodium and water, which can help lower blood volume as well. Therefore, the net effect of Enalapril Maleate in managing hypertension is a decrease in blood pressure, making it a crucial medication in the management of this condition.

Other answers reflect effects that would generally move in the opposite direction of what is intended in hypertension management. For example, an increase in blood volume or heart rate is typically associated with raising blood pressure, while reduced vascular elasticity would contribute to increased resistance in blood vessels. Thus, the focus on a decrease in blood pressure highlights the primary therapeutic goal of using Enalapril in treating hypertension.

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