What are common adverse drug reactions for Isosorbide Mononitrate?

Isosorbide mononitrate is a medication primarily used to prevent angina (chest pain) in patients with coronary artery disease. The drug works as a nitrate, which helps to relax and widen blood vessels, thus improving blood flow and reducing the heart's workload.

Dizziness and headache are common adverse drug reactions associated with isosorbide mononitrate. The mechanism behind these side effects is related to the vasodilatory effects of the medication. As blood vessels dilate, blood pressure can decrease, leading to dizziness, particularly upon standing or with abrupt changes in position. Headaches often occur due to the increased blood flow and pressure changes within the cranial vasculature triggered by the medication’s effects.

These adverse reactions are important for healthcare providers and patients to be aware of, as they can impact the patient's quality of life and their ability to perform daily activities. Monitoring and managing these effects is essential for ensuring the patient's adherence to therapy.