What are common adverse drug reactions associated with Metronidazole?

Metronidazole is primarily used as an antibiotic and antiprotozoal medication. Among the various common adverse drug reactions associated with its use, headaches and nausea are prevalent. Headaches can occur due to the drug's central nervous system effects, and nausea is often experienced as part of its gastrointestinal side effects. This combination is particularly significant because they can affect patient compliance with the treatment regimen, as these symptoms may lead to discontinuation of the medication.

While rash and itching can occur with many medications, they are not as commonly associated with Metronidazole. Drowsiness and dry mouth are less frequently reported side effects of this medication, making them less typical adverse reactions. Fatigue and anemia are generally more related to long-term use or specific patient conditions rather than the most common reactions seen with Metronidazole. Thus, headaches and nausea stand out as the most frequently observed adverse effects linked to this antibiotic.