What are patients advised to watch for when taking Losartan regarding fluid loss?

When taking Losartan, patients are advised to watch for excessive fluid loss because it can lead to hypotension (low blood pressure). Losartan is an angiotensin II receptor blocker (ARB) that helps to lower blood pressure by blocking the effects of angiotensin II, which can cause blood vessels to constrict. This medication can also impact kidney function and fluid balance. If patients experience significant fluid loss, it may exacerbate the blood pressure-lowering effect, putting them at risk for dizziness, fainting, or other complications related to dehydration and low blood volume.

Monitoring for excessive fluid loss becomes particularly important for patients who may already have conditions that predispose them to dehydration or low blood pressure, such as those on diuretics, elderly patients, or individuals with significant gastrointestinal losses. Thus, it is essential for patients to be aware of and report any symptoms of dehydration, such as excessive thirst, reduced urine output, or dizziness.