What box warning is associated with Enalapril Maleate?

Enalapril Maleate is an ACE inhibitor used primarily for managing hypertension and heart failure. The box warning associated with this medication specifically highlights the risks of using it during pregnancy. Enalapril can cause injury and even death to the developing fetus when administered during the second and third trimesters. This warning is crucial as it underscores the importance of avoiding ACE inhibitors in pregnant patients due to the potential for serious adverse outcomes.

In contrast, the other options do not pertain to the known serious risks of Enalapril. There is no box warning related to an increased risk of cardiovascular disease or arrhythmias specifically tied to its use. Additionally, Enalapril does not possess addictive properties, rendering the option regarding potential for addiction irrelevant in the context of its safety profile. Thus, the warning about pregnancy is essential for healthcare professionals to recognize to ensure safe prescribing practices.