What common adverse drug reaction is associated with Fenofibrate?

Fenofibrate is primarily known for its role in lowering cholesterol and triglyceride levels, and it does come with a range of potential adverse drug reactions. One of the most commonly reported adverse effects of Fenofibrate is gastrointestinal discomfort, which can include symptoms like abdominal pain, nausea, and diarrhea.

The association of Fenofibrate with muscle pain or myopathy is also significant, particularly because it can lead to a rare but serious condition known as rhabdomyolysis, especially when used in combination with statins. Although hyperhomocysteinemia, which refers to elevated levels of homocysteine in the blood, is more commonly associated with certain deficiencies (like vitamin B12 or folate deficiency) rather than being directly linked to Fenofibrate, gastrointestinal discomfort remains a more commonly recognized side effect based on clinical observation and reports.

Furthermore, while allergic reactions can occur with any medication, they are not predominant in the landscape of side effects typically noted with Fenofibrate. The prevalence and recognition of gastrointestinal discomfort as a side effect make it a significant point of consideration when prescribing this medication.