What critical warning is associated with the use of Lisinopril?

Lisinopril carries a critical warning regarding its use during pregnancy. It belongs to the class of medications known as ACE inhibitors, which have been shown to pose significant risks to the developing fetus, particularly in the second and third trimesters. These risks include fetal injury or even death, as ACE inhibitors can lead to issues such as renal failure, oligohydramnios, and pulmonary hypoplasia in the unborn child. It is thus crucial to avoid prescribing Lisinopril to women who are pregnant or may become pregnant, and healthcare providers typically recommend alternative treatments that are safer during pregnancy.

The other warnings associated with Lisinopril, such as potential liver damage or implications for patients with heart failure, do exist but are not as critical or urgent as the risks involved when used during pregnancy. Additionally, Lisinopril does not present a risk of addiction. Understanding the implications of medication use in different populations, particularly pregnant women, is essential for safe prescribing practices.