What is a key patient counseling point regarding the administration of Isosorbide Mononitrate?

Isosorbide Mononitrate is a medication primarily used for the prevention of angina pectoris due to coronary artery disease. A crucial counseling point for patients taking Isosorbide Mononitrate is that it should be taken on an empty stomach, typically one hour before or two hours after a meal. This is important because food can affect the absorption of the medication, potentially reducing its efficacy in relieving symptoms of angina. Taking the drug on an empty stomach ensures that the patient receives the maximum benefit from the medication.

Effective absorption is vital for Isosorbide Mononitrate to work properly since it acts as a nitrate to dilate blood vessels and improve blood flow to the heart. Hence, adherence to this guideline helps optimize therapeutic outcomes and may reduce the frequency or severity of angina attacks.