What is a potential side effect of Chlorthalidone?

Chlorthalidone, a thiazide-like diuretic used primarily for hypertension and edema, can lead to various side effects, one of which is hyperuricemia. This condition occurs due to the drug’s mechanism of action that can increase uric acid levels in the blood.

Thiazide diuretics, including Chlorthalidone, can decrease the renal excretion of uric acid. As a result, patients may experience elevated uric acid levels, potentially leading to gout or worsening of gout symptoms in predisposed individuals. Understanding this mechanism highlights the importance of monitoring uric acid levels in patients receiving this medication, especially those with a history of gout.

The other side effects mentioned in the options are also important to consider, but hyperuricemia is particularly characteristic of the action of Chlorthalidone. Thus, recognizing its potential to elevate uric acid levels is crucial for managing patient care effectively.