What is Spironolactone's pregnancy category?

Spironolactone is classified as a pregnancy category C medication. This category indicates that animal reproduction studies have shown an adverse effect on the developing fetus, but there are no adequate and well-controlled studies in pregnant women. It suggests that the benefits may outweigh the risks in certain situations, but caution is warranted. Spironolactone is generally not recommended for use in pregnancy unless the benefits to the mother outweigh potential risks to the fetus.

The options for categories A and X are not appropriate for spironolactone. Category A indicates that studies in pregnant women have not demonstrated a risk to the fetus in the first trimester, while category X signifies that the drug is contraindicated in pregnancy due to evidence of fetal risks. These designations do not apply to spironolactone, reinforcing that category C is the most accurate classification. Therefore, while "none" could imply an incorrect understanding of its classification, the correct answer highlights the need for awareness of its potential risks during pregnancy.