What is the main concern regarding the use of Losartan Potassium during pregnancy?

Losartan Potassium, an angiotensin II receptor blocker, is indeed contraindicated during pregnancy primarily due to its potential to harm the developing fetus. The use of Losartan, particularly in the second and third trimesters, can lead to serious adverse effects, including fetal renal impairment, reduced amniotic fluid, and can result in complications such as hypotension and even fetal death. This is because medications that interfere with the renin-angiotensin system can disrupt normal fetal development and lead to significant health risks.

Given these risks, healthcare providers strongly advise against the use of Losartan and similar medications during pregnancy. Awareness of the potential for teratogenic effects and the overall impact on fetal health is crucial for expectant mothers, which is why the use of this medication is viewed with such caution in this context.