What is the primary boxed warning associated with Warfarin?

Warfarin has a primary boxed warning that highlights the significant risk of bleeding associated with its use. This blood thinner is designed to prevent blood clots, but it also increases the risk of both minor and major bleeding events due to its anticoagulant properties. This is critically important for healthcare providers and patients to understand, as the management of anticoagulation therapy requires careful monitoring and dosing to maintain safe levels and prevent adverse effects.

Understanding the risk of bleeding helps clinicians and patients recognize symptoms of hemorrhage and emphasizes the importance of regular INR monitoring to adjust dosing appropriately. Other options, while they may be relevant to different medications, do not capture the primary concern tied specifically to Warfarin. The risk of bleeding is the most significant and immediate threat linked to its use, thereby necessitating the boxed warning to inform and guide treatment practices.