What is the recommended time for taking Hydrochlorothiazide to avoid nocturia?

Taking Hydrochlorothiazide early in the day is recommended to minimize the risk of nocturia. Hydrochlorothiazide is a diuretic often prescribed for conditions such as hypertension and edema. Diuretics work by promoting the elimination of excess fluid through urine. When taken early in the day, the medication allows for increased urination to occur during waking hours, thus reducing the chances of needing to get up at night to urinate.

If taken close to bedtime, there is a higher likelihood that the medication will lead to increased urine production during the night, resulting in nocturia. Therefore, scheduling the dose in the morning or early afternoon helps avoid disruptions to sleep associated with nighttime urges to urinate.