What potential side effect should patients report when starting Metoprolol?

When starting Metoprolol, a beta-blocker commonly prescribed for conditions such as hypertension and heart issues, it is particularly important for patients to be aware of the potential for exacerbation of angina. This side effect can occur because while beta-blockers are designed to decrease heart workload and oxygen demand, they may not be the best choice for everyone, especially in patients with certain types of angina or unstable coronary artery disease. If the medication causes a decrease in heart rate or a drop in blood pressure that is too significant, it can lead to insufficient blood flow to the heart muscle, potentially worsening angina symptoms.

Patients should be vigilant about monitoring their symptoms and report any worsening of chest pain or angina episodes to their healthcare provider promptly. This precaution is necessary because an exacerbation of angina can indicate that the medication may not be effectively managing the patient's heart condition or may require a reevaluation of their treatment plan.

The other options are generally less associated with Metoprolol. Increased appetite, joint pain, and headaches can arise from various factors or medications but are not primary concerns linked to starting Metoprolol. Thus, reporting exacerbation of angina is critical for ensuring the safety and effectiveness of treatment.