What pregnancy category is assigned to hydralazine hydrochloride?

Hydralazine hydrochloride is assigned a pregnancy category of C. This classification means that animal reproduction studies have shown an adverse effect on the fetus, and there are no adequate and well-controlled studies in pregnant women. However, the potential benefits of using the drug in pregnant women may warrant its use despite potential risks.

In contrast, a category of A indicates controlled studies in pregnant women showing no risk, while category B denotes no evidence of risk to fetuses based on animal studies, but insufficient data in humans. A category of D indicates positive evidence of human fetal risk but may be justified in certain situations. Since hydralazine hydrochloride falls under category C, this distinguishes it from the other classifications and clarifies that while there may be risks, it can sometimes be deemed necessary for treating certain conditions during pregnancy. Thus, the correct classification of hydralazine hydrochloride reflects a balanced understanding of the potential risks and benefits in the context of pregnancy.