What should be done to extended-release formulations of Potassium Chloride before consumption?

Extended-release formulations of Potassium Chloride must be handled correctly to ensure their effectiveness and safety. These formulations are specifically designed to release the active ingredient slowly over time rather than all at once, which helps to maintain stable potassium levels and minimizes the risk of gastrointestinal side effects.

Choosing to break an extended-release formulation may be appropriate only if the product is specifically manufactured to allow this; for instance, some extended-release tablets have a scoring line indicating they can be split without affecting the release mechanism. It is essential to check the manufacturer's instructions or consult with a pharmacist when unsure. However, crushing or altering the tablet in other ways compromises the integrity of the extended-release system, potentially leading to rapid release of potassium, which can cause hyperkalemia and other side effects.

Therefore, Potassium Chloride extended-release formulations should only be manipulated as indicated by the manufacturer's guidelines.