What therapeutic classification does Furosemide belong to?

Furosemide is classified as a Loop Diuretic. This therapeutic classification indicates that Furosemide primarily acts on the loop of Henle in the nephron, the functional unit of the kidney. By inhibiting the sodium-potassium-chloride cotransporter in this area, Furosemide effectively increases urine output by promoting diuresis and helps reduce fluid overload in conditions such as congestive heart failure, renal impairment, and hypertension.

The loop diuretic classification also differentiates it from other types of diuretics, such as thiazide diuretics, which primarily work on the distal convoluted tubule, potassium-sparing diuretics that help retain potassium while promoting diuresis, and osmotic diuretics that rely on the osmotic pressure to draw water into the urine. Furosemide's mechanism of action and its potent efficacy in promoting diuresis make it a critical medication in managing various cardiovascular and renal conditions.