Which common adverse drug reaction is associated with clindamycin?

Clindamycin is commonly associated with diarrhea as an adverse drug reaction. This occurs because clindamycin is a broad-spectrum antibiotic that can disrupt the normal flora of the gut, potentially leading to overgrowth of Clostridium difficile, a bacterium that can cause serious gastrointestinal issues, including antibiotic-associated diarrhea and colitis.

While nausea, headache, and insomnia can be potential side effects of various medications, they are not as specifically linked to clindamycin as diarrhea is. The understanding of this mechanism is important for both healthcare providers and patients, as it underscores the necessity for monitoring gastrointestinal symptoms during treatment with clindamycin and provides an insight into patient education regarding the potential side effects of antibiotics.