Which condition is Ezetimibe indicated for?

Ezetimibe is primarily indicated for the management of elevated cholesterol levels, specifically in patients with familial hypercholesterolemia, whether homozygous or heterozygous. This condition is a genetic disorder characterized by high cholesterol levels, which can lead to an increased risk of cardiovascular disease. Ezetimibe works by inhibiting the absorption of cholesterol from the intestine, thereby lowering overall cholesterol levels, making it particularly useful for these patients.

In the context of the other conditions listed, hypertensive heart disease focuses on managing high blood pressure rather than cholesterol, making Ezetimibe inappropriate. Type 2 diabetes management generally involves a different class of medications aimed at controlling blood glucose rather than cholesterol. Atrial fibrillation is an arrhythmia that may necessitate anticoagulation or rate/rhythm control, none of which directly involves Ezetimibe. Therefore, its specific indication for familial hypercholesterolemia-homozygous distinguishes it as the correct choice.