Which is a common adverse drug reaction of Enalapril Maleate?

Study for the 2PD Top 200 Drugs Anti-Infectives and Cardiovascular Agents Test. Access flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Enalapril maleate is an ACE (Angiotensin-Converting Enzyme) inhibitor commonly used to treat hypertension and certain types of heart failure. One of the notable adverse drug reactions associated with Enalapril is an increase in serum creatinine (SCr) levels. This reaction occurs due to the medication's effect on the renal blood flow, particularly in patients who may have pre-existing renal impairment or those who are volume-depleted.

Monitoring kidney function, including serum creatinine, is essential when initiating or adjusting therapy with Enalapril, as significant changes in renal function could lead to complications. Although a normal elevation in SCr is typically mild and reversible upon discontinuation or dose adjustment, it's critical for healthcare providers and patients to be aware of this potential effect.

Other possible adverse effects, such as a dry cough, are also commonly associated with ACE inhibitors. However, in this context, the most pertinent and significant laboratory finding that patients might exhibit while on Enalapril is the increase in serum creatinine due to its implications for renal function.

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