Which of the following is an example of a common adverse drug reaction to hydrochlorothiazide?

Hydrochlorothiazide is a thiazide diuretic commonly used to manage hypertension and fluid retention. One of the well-known adverse drug reactions associated with this medication is hypotension. This occurs because the drug works by inhibiting sodium reabsorption in the kidneys, leading to increased urine output and subsequently reducing blood volume. When blood volume decreases, it can result in lower blood pressure, which is classified as hypotension.

While other options may occur with some medications or in certain contexts, hypotension is particularly relevant to hydrochlorothiazide due to its pharmacological effects on fluid and electrolyte balance, making it a significant adverse reaction to monitor in patients using this medication.