Which of the following is a therapeutic classification for Hydrochlorothiazide and Losartan Potassium?

The correct therapeutic classification for Hydrochlorothiazide and Losartan Potassium is that they belong to a thiazide diuretic and an angiotensin II receptor antagonist, respectively. Hydrochlorothiazide is well-known for its diuretic properties, which help to decrease blood pressure by promoting the excretion of sodium and water. This mechanism decreases blood volume and, consequently, blood pressure.

Losartan Potassium is classified as an angiotensin II receptor antagonist. It works by blocking the effects of angiotensin II, a hormone that can cause blood vessels to constrict and increase blood pressure. By inhibiting this action, Losartan helps to relax blood vessels and further lower blood pressure.

This combination is often used in clinical practice to manage hypertension effectively, as they work synergistically to reduce blood pressure. The use of a diuretic alongside an angiotensin II receptor antagonist helps to address both fluid retention and vascular resistance in hypertensive patients.

The other classifications do not fit the medications mentioned; for instance, thiazide diuretics and beta-blockers do not include Losartan, and the calcium channel blockers or ACE inhibitors are entirely different drug classes. Thus, the pairing of Hydrochlorothiazide and Losartan