Which side effect of Prazosin is especially noted for older patients?

Postural hypotension is notably a significant concern for older patients taking Prazosin. This medication, primarily used to treat hypertension and symptoms of benign prostatic hyperplasia, can cause a drop in blood pressure when the patient moves from a sitting or lying position to standing. This condition is particularly risky for older adults because they may already have compromised cardiovascular health, dehydration risks, or be on multiple medications that affect blood pressure regulation.

In older patients, the physiological changes associated with aging can exacerbate the effects of Prazosin, making them more susceptible to dizziness, lightheadedness, and even fainting when standing up quickly, thereby increasing the risk for falls and related injuries. The importance of closely monitoring for this side effect in older adults cannot be overstated, as it directly impacts their safety and quality of life.